Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role ...

Cells are constantly on the move, whether in a developing embryo or metastatic cancer. But how do cells adapt to the new ...

Pulmonary hypertension, despite advances in treatment, still has a poor prognosis, which is often associated with right heart failure, and for which pulmonary arterial hypertension (PAH) is a severe ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

These immature myeloid cells inhibit the proliferation and induce apoptosis of activated T cells. Targeted depletion of granulocytic MDSC (Gr-MDSC) in autochthonous PDA increases the intratumoral ...

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Deregulated apoptosis may also be the leading cause ... 11 and -12), which allow for interactions with other proteins, and link with signalling pathways. In another study, the sensitivity of NSCLC and ...