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Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.
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The first patient with Cyclin E1+ platinum-resistant ovarian cancer has been dosed with azenosertib in part 2a of the phase 2 ...
The bispecific T-cell engager tarlatamab demonstrated favorable antitumor activity in a small cohort with small cell lung ...
Cancer continues to pose a substantial public health problem in Nigeria, characterized by rising rates of occurrence and ...
Following promising phase 1 data, ISB 2001 has gained fast track designation from the FDA for the treatment of ...
This valuable study provides insights into a key question in comparative neuroanatomy and development. The authors provide evidence of the role for a particular micro-RNA in regulating the development ...
A new study highlights a potential role for immune system dysfunction in the onset and progression of Alzheimer's disease.