“The cell cycle has been studied intensively for decades, and here we’ve found it working in a new way,” said Jeremy Reiter, PhD, UCSF professor of biophysics and biochemistry and senior author of the ...

To understand the dynamics of cell-cycle status in tumors, Florian’s team used two new reporters: one to visualize G1 and the other to see G2, S, and M phases. “Because [FUCCI4] uses fluorescent ...

Study overturns 'snapshot' model of cell cycle in use since 1974 Date: April 2, 2020 Source: University of Colorado Anschutz Medical Campus Summary: Live, single-cell imaging shows cellular ...

The cell cycle is a mechanism that controls and integrates the stages of DNA synthesis, mitosis, and cell division. This mechanism dictates growth and development, as well as reproduction.

They applied a relatively new tool, the fluorescent ubiquitination-based cell-cycle indicator (FUCCI), to cultured mouse neurons to reveal those that re-engaged the cell cycle. At any given time, ...

Cell cycle speed is key to making aging cells young again Date: January 30, 2014 Source: Yale University Summary: Researchers identified a major obstacle to converting cells back to their youthful ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

These patterns of macromolecule production timing during the cell cycle are relevant contributions, said Nicolas Buchler, a biophysicist at the North Carolina State University who was not involved in ...

Somatic cell cycle consists of four phases while early embryonic cell cycle alternates between S and M phases without intervening G1 and G2 phases.

Mammalian cyclins and cyclin-dependent kinases (CDKs) have non-canonical, cell cycle-independent functions in processes such as transcription and DNA damage repair. Through these and other ...