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Nature7mon
Neuroprotection by a caspase inhibitor in acute bacterial meningitis
Z-VAD-fmk blocks hippocampal neuronal loss. The peptide z-VAD-fmk is a broad-spectrum caspase inhibitor that effectively delays apoptosis in many cell types 14,15,16.To assess its potential ...
ascopubs.org10y
Pan-caspase peptide inhibitor to induce primary chronic lymphocytic leukemia (CLL) cell death through a non-apoptotic and non-necroptotic mechanism.
TREAT-ME 1: Treatment of advanced gastrointestinal cancer in a clinical phase I/II trial with genetically modified mesenchymal stem cells: Clinical results of a phase I study. An open-label, ...
Business Wire2y
Amerimmune LLC Maintains Intellectual Property on the COVID-19 Related Use of Caspase Inhibitors as a Result of Histogen Inc. Led Arbitration - Business Wire
Amerimmune LLC Maintains Intellectual Property on the COVID-19 Related Use of Caspase Inhibitors as a Result of Histogen Inc. Led Arbitration January 18, 2023 02:02 PM Eastern Standard Time ...
Business Insider7y
Conatus Pharmaceuticals Announces Upcoming Oral Presentation at EASL Annual MeetingPan-caspase Inhibitor IDN-7314 Reduces Inflammation and Liver Injury in ... - Markets Insider
SAN DIEGO, April 09, 2018 (GLOBE NEWSWIRE) -- Conatus Pharmaceuticals Inc. (NASDAQ:CNAT), a biotechnology company focused on the development of ...
The Scientist1y
Multiplexing Caspase-Based Apoptosis Assays with Automated Microscopy
Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark of apoptosis initiation—with fluorescent dyes. Researchers often perform multiplex caspase assays ...