Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis ...
Luminescent gold nanoparticles (L-AuNPs) represent a novel class of luminescent nanomaterials that have attracted ...
Blockade of caspase-3, but not inhibition of tyrosine kinase dependent pathways, prevented the alterations in TJ protein expression and permeability induced by the Fas/FasL system in human alveolar ...
A study published in the European Journal of Trauma and Emergency Surgery found that cannabidiol (CBD) may help mitigate lung ...
Prof. MENG Guangxun's team from the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences, and collaborators, have revealed a novel mechanism whereby a short form of IL-18, ...
A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage in tumor cells, activates natural killer (NK) cells to suppress tumor ...
Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway remains largely uncharacterized. We show here that Fas kills activated primary T cells ...
The study also opens new avenues for treatment. Medications that inhibit IL-1β or caspase-1—the enzyme that activates IL-1β production—are promising candidates to prevent AF in at-risk patients, ...
Nature Immunology is a multidisciplinary journal that publishes papers of the highest quality and significance in all areas of immunology. Priority is given to work that provides fundamental ...
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