Inflammasomes are assemblies that are central to inflammatory responses. Now researchers shed new light on function of caspase 12. They have rid the field of a stubborn dogma, which held that caspase ...
Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program. This type of cell death is referred to as "programmed cell death". Until ...
Tau tangles are a hallmark of Alzheimer’s disease and other tauopathies, but how these aggregates relate to cognitive decline remains a mystery. Writing in the October 10 Nature Medicine, researchers ...
Impact of microsatellite instability status and sidedness of the primary tumor on immunophenotype of colorectal cancer. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...
Caspases are proteases: enzymes that catalyze the breakdown of proteins and are part of the cysteine–aspartic acid protease family. They are vital to the mechanism of programmed cell death in animals ...
Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...
Dragon’s blood, a traditional Chinese medicine resin, shows promise in treating ulcerative colitis (UC). Research identified ...
New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants. The research by Ailong Ke, the ...
From Bambino Gesù Children's Hospital in Rome comes a report that a third-generation CAR T cell therapy targeting GD2, designated GD2–CART01, induced durable remissions and long-term survival in ...
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