A 55-year-old woman with a history of scleroderma presented after 5 days of experiencing fever, chills and progressive swelling of her right thumb (Fig. 1). The thumb was exquisitely tender to touch.

Despite the use of angiotensin-converting enzyme inhibitors to prevent scleroderma renal crisis (SRC), it occurs in 6% of all patients with SSc, and in 10–15% of those with diffuse SSc; 40% of ...

Calcinosis Calcinosis is a condition that manifests as calcium deposits in the skin and other tissues of the body. Common causes include trauma, acne, varicose veins.

Bob Saget. Mike Coppola/Getty Scleroderma is a rare, autoimmune connective tissue and rheumatic disease that primarily causes inflammation in the skin, and can lead to inflammation in other parts ...

More than 95% of people with scleroderma have both Raynaud's phenomenon and skin thickening (also called sclerodactyly when the fingers are involved). In addition, those with limited scleroderma ...

An estimated 200,000 Americans have scleroderma, about 80,000 of whom have the systemic form of the disease, known as systemic sclerosis (SSc). SSc is further sub-classified as diffuse cutaneous ...

Scleroderma, also sometimes referred to as systemic sclerosis, is a chronic autoimmune disorder that involves progressive hardening of the skin. An excess of collagen and other connective tissues ...

Bob Saget attends The Scleroderma Research Foundation's Cool Comedy - Hot Cuisine at San Francisco Palace Hotel on April 29, 2009, in San Francisco, California. (Steve Jennings/WireImage) ...

Among patients with juvenile dermatomyositis, calcinosis was associated with longer active disease duration, disease severity and clinical features such as lipodystrophy and joint contractures ...

The Scleroderma Research Foundation (SRF), a 501 (c) (3) organization, was established in 1987 with a mission to fund and facilitate the most promising, highest quality research aimed at new ...