eLife3d
Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection
This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...
Medscape17d
How High should the CD4 Cells Go?
Among the most common: What is a "good" T-cell response to effective therapy? How high "should" the CD4-cell count rise in order to minimize AIDS-related morbidity and mortality? To find answers ...
Yahoo18d
Red tide raging in Gulf as cell counts hit 20 million cells per liter off Sanibel
Red tide cell counts are well into the "death zone" in Lee ... a shorebird expert with Audubon Florida. "It usually doesn't affect the shorebirds too heavily at first. The cormorants and the ...
The New England Journal of Medicine18d
CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in TP53
S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...
BMJ19d
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression
Objectives To study the biology of the conventional T cells in human enthesis. Methods CD4+ and CD8+ T cells were investigated in 25 enthesis samples using immunofluorescence, cytometrically, bulk ...
Frontiers20d
Pathogenesis and novel therapeutics of regulatory T cell subsets and interleukin-2 therapy in systemic lupus erythematosus
Natural arising CD4+ regulatory T cells (Tregs) play a critical role in maintaining peripheral tolerance by suppressing inflammation and preventing autoimmune responses in SLE. Additionally, CD8+ ...
Frontiers20d
Your Regulatory T Cells Are What You Eat: How Diet and Gut Microbiota Affect Regulatory T Cell Development
Treg represent a highly heterogeneous population of immunosuppressive immune cells contributing to peripheral tolerance. Tregs either develop in the thymus from autoreactive thymocytes, or in the ...
The Tribune24d
White blood cell count may predict severity of COVID-19: Study
However, a new study reveals that leukocyte (white blood cell) count may now be used to identify who is more likely to develop more significant disease symptoms. The Tribune, now published from ...
healthday25d
Long COVID Severity Linked to White Blood Cell Count
WEDNESDAY, Jan. 29, 2025 (HealthDay News) -- A simple blood test might determine which patients are at ... and to verify the link between white blood cell counts and long COVID risk, researchers said.