The absolute CD4 count is a measurement of how many functional ... which assesses the number of CD4 T-cells compared to the number of CD8 T-cells. With the test, your doctor can see if the disease ...

Among the most common: What is a "good" T-cell response to effective therapy? How high "should" the CD4-cell count rise in order to minimize AIDS-related morbidity and mortality? To find answers ...

Here we have designed a CAR, CD4CAR, which redirects the antigen specificity of CD8+ cytotoxic T cells to CD4-expressing cells ... in order to maintain T-cell counts <2 × 10 6 cells/ml.

S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

We show herein that primary in vitro stimulation of CD45RA-selected CD4 T cells of stem-cell donors with 10/10 HLA-matched AML blasts results in expansion of cytolytic T-lymphocytes (CTL ...