We found that dorsal CA1 and dentate gyrus neurons are vulnerable to elevated expression of DLK, while CA3 neurons appear less vulnerable. We identified the DLK-dependent translatome that includes ...

Here, they extend this work to show that inducible over-expression in Vglut1+ neuron also kills excitatory neurons in hippocampal CA1, but not CA3. They complement this very interesting finding with ...

Although SWRs are composite events, the sharp wave and ripple components are functionally distinct: the sharp wave is an excitatory potential transmitted from the hippocampal CA3 to the CA1 subregion, ...

Subsequently, mossy fibers originating from the DG terminate in both the DG and CA3. From the CA3, fibers known as Schaffer collaterals project to CA1. Ultimately, CA1 sends outputs to the subiculum ...

Today, there will be thick cloud in the early morning. As the day draws on, the cloud will break up from the south, with sunny spells widely developing in the afternoon. Breezy and slightly milder ...

Despite being a first-line treatment for adolescent depression and anxiety, antidepressant drugs appear to have questionable efficacy and carry an increased risk of adverse effects in this ...

U.S. President Donald Trump still plans to enact 25 per cent tariffs on goods from Canada and Mexico starting this weekend, the White House said Tuesday. Speaking at the first press briefing of ...

The federal government will lend $1 billion to Canada Post for the 2025-26 fiscal year so that it can continue operating while dealing with "significant financial challenges," the postal service ...

Soldiers on the front lines with Ukraine’s 80th Air Assault Brigade spoke to CBC News using their call signs, as allowed under Ukrainian military rules. From left: Voodoo and Chapi, two foreign ...

Here’s how much the super-rich are really worth Mark Cussen, CMFC, has 13+ years of experience as a writer and provides financial education to military service members and the public. Mark is an ...