The trial tested two doses of claseprubart -- 300 mg and 600 mg -- and its primary endpoint was safety. Secondary outcomes included scores on the Myasthenia-Gravis Activities of Daily Living (MG-ADL) ...

Claseprubart achieved statistically significant and clinically meaningful improvements in Myasthenia Gravis Activities of Daily Living (MG-ADL), ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Dysregulated proteolysis is central to ...

Immunotherapy is increasingly becoming standard therapy in cancer, with technology, such as checkpoint inhibitors and cell therapy, raising the efficacy bar in many forms of the disease. But the ...

Figure 1: Oncoantigens are on tumour cells and the tumour microenvironment. Subject to these caveats, transgenic mouse strains that express oncogenes that cause autochthonous cancer can be studied to ...

Protection of self cells is conferred principally by intrinsic cell surface regulators. These molecules are the decay-accelerating factor (DAF or CD55), membrane cofactor protein (MCP or CD46), and ...

The biggest trap curvy women fall into is reaching for baggy, oversized pieces thinking they'll hide problem areas. It's no surprise that the most common fashion mistake curvier women make is wearing ...