For example, the HNH domain was fused to the C-terminus of Cas5, replacing the need for Cas3, a protein commonly involved in DNA degradation in other systems. This structural innovation pointed to ...

With the exception of red blood cells, which contain no nucleus and no nuclear DNA, every one of these cells contains the human genome -- a string of three billion A's, C's, G's, and T's.

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...