The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...

Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in n.

Smith, Ph.D., and a team of researchers investigated methods to accurately measure drug permeability across the blood-brain barrier. For decades ... considers themselves studying drug delivery in vivo ...

Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...

The findings revealed a novel mechanism through which microplastics indirectly disrupt vascular and neurological functions without crossing the blood-brain barrier ... in vivo, are poorly understood.

glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 involvement in these processes, as shown from numerous in vitro and in vivo studies that ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...

This includes the most complex systems like the blood-brain barrier, which is a significant ... In humans/animals (In Vivo): Sometimes, they test the drug in a living body to see how it works.

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

The blood–brain barrier acts as a highly selective shield that protects the brain from harmful substances in the bloodstream. However, this same protective feature makes it difficult for most ...