The image also highlights chemical modifications (yellow) that increase durability, and biotin molecules that help anchor the aptamers to surfaces or other molecules in sensors and assays. (Image: ...
It is doubly biotinylated at its 5′ end and has a PEG 18 spacer and a thymidine base between the biotins and the Tag1 sequence, for example, 5′-Dual biotin-Spacer18-T-TCCCGCGAAATTAATACGAC-3′.
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