Recognition of specific antigen through the B-cell receptor (BCR ... are specialized to maximize the probability of lymphocytes encountering their specific cognate antigen, which is provided ...

Chronic lymphocytic leukemia (CLL) is a mature B-cell hematological malignancy characterized by progressive clonal proliferation of B lymphocytes in the peripheral blood, bone marrow, and lymph nodes.

This cancer affects immature cells in the immune system called prolymphocytes, which usually develop into white blood cells called lymphocytes. In B-PLL, B-lymphocytes grow and divide excessively ...

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML ...