With several antibodies to mop up amyloid plaques coming into routine use, the big challenge for scientists has become to find ways to temper tau pathology. Two different studies report some news on ...
ABSTRACT: Vacuolar H⁺-ATPase (V-ATPase), encoded by the ATP6V gene family, is an evolutionarily conserved, a multisubunit proton pump that plays a fundamental role in maintaining intracellular pH ...
Using leading-edge technology, neuroscientists at Beth Israel Deaconess Medical Center (BIDMC) gained new insight into the brain circuitry that regulates water and food intake. In a new study, the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Reduced autophagy is associated with the ...
TAINAN, June 12, 2025 /PRNewswire/ -- Merry Life Biomedical Company announces the launch of its global Phase II clinical trial for TML-6, a novel oral small molecule drug targeting early-stage ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste. This process, known as autophagy, is like a ...
We have shown previously that FoxO1, a member of the FoxO transcription factor family, is upregulated by nutrient starvation and cardiac unloading. FoxO1 in turn promotes autophagy, thereby mediating ...
Non-invasive minimal residual disease detection of liver cancer using circulating tumor DNA features and α-fetoprotein: A prospective study. The association between TAS2R gene expression and ACC ...
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