Atg5 has been previously characterized as a protein specifically required for autophagy, a lysosomal catabolic pathway for proteins and organelles. However, it has now been shown that, in addition ...

Atg5, an autophagy protein is cleaved by calpain 1, 2 into truncated Atg5 (tAtg5), tAtg binds to Bcl-xl and leads to apoptosis. Full size image. Bcl-2 and Autophagy.

More information: Janine Tutas et al, Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic ...

Autophagy is a cellular process performed by cells for ... and VMP1, cooperate, along with the catalyzation of two conjugation reactions by Atg7. First, Atg5 and Atg12 – which are conjugated ...

The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful. However, ...

The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful. However, ...

Living; Study shows exercise increases autophagy, that is, it renews old parts of your cells. Published: ; Apr. 05, 2012, 9:30 a.m.

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell ...

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has ... Atg5-deficient dendritic cells significantly elevated receptor CD36 on the surface of ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

Autophagy also has been linked to anti-aging benefits, Dr. Trinh says. As people age, autophagy can decrease, which causes a build-up of junk from cells, keeping them from functioning at their best.