Suspecting that autophagy might promote the use of HR over error-prone repair pathways, the research team investigated its effect on gene editing. When autophagy was triggered—either by nutrient ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

In this study, the authors show that autophagy controls blood cell differentiation in a Drosophila model of hematopoiesis. Notch activation depends on the endocytic pathway and promotes crystal ...

Wound healing is a huge challenge for medicine that enhances tissue regeneration and macrophage reprogramming. However, current therapies do not coordinate tissue regeneration and macrophage ...

34. Liu X, Tang J, Peng L, Nie H, Zhang Y, and Liu P. Cancer-associated fibroblasts promote Malignant phenotypes of prostate cancer cells via autophagy: Cancer-associated fibroblasts promote prostate ...

Vorinostat successfully induced autophagy by increasing ATG9B, ATG16L1, ATG5, and ATG4C expression and decreasing the accumulation of LC3-II/I. Additionally, we observed that SAHA promotes the fusion ...