A mutation in FBXO31 that replaces an aspartate with an asparagine residue (a D334N mutation ... that are required for normal cellular function. Control of human protein-degradation machinery ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

The liver performs hundreds of vital functions, including converting nutrients from food into energy, filtering toxins from the blood, and producing bile, a key substance in digestion and waste ...

A Potential Solution for Neurodegenerative Diseases. Open Access Library Journal, 12, 1-16. doi: 10.4236/oalib.1112714 . Alzheimer’s Disease (AD), a complex neurodegenerative condition, significantly ...

Do you hike in the mountains, swim in the ocean, watch the sunset or listen to birds? Do you wish the outdoors were easier to access where you live? By Natalie Proulx What is it like to report ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Despite the effectiveness of biofertilizers, when applied ...

Most virus infections can alter the autophagy level, which functions as either a pro-viral or antiviral pathway, depending on the virus and host cells. Singapore grouper iridovirus (SGIV) is a novel ...

1 The realisation that proteins are heavily modified, and that these modifications are critical to their structure and function, has led to a shift in emphasis from primarily studying genes and ...

In a mouse model of scopolamine-induced memory impairment, CP enhances anti-inflammatory function by inhibiting TNF-α, IL-6 and regulating intestinal flora (Xie et al., 2024). In traditional Chinese ...

Objective Polymorphisms in the antifungal signalling molecule CARD9 are associated with ankylosing spondylitis (AS). Here, we investigated the cellular mechanism by which CARD9 controls pathogenic ...