How M. tuberculosis alters host cell death mechanisms to facilitate infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
Armed robbery in Revesby4d
Bacterial Effector Alters Host Cell Death to Aid Infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis ...
Nature16d
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Cell death is achieved by two fundamentally different mechanisms: apoptosis and necrosis. Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway ...
Frontiers19d
RhoA/ROCK Signaling Regulates Drp1-Mediated Mitochondrial Fission During Collective Cell Migration
The dynamic network of mitochondria in individual cells is regulated by mitochondrial fission and fusion, and is required for cellular processes including cell metabolism, apoptosis and cell division.
Nature20d
Apoptosis in animal models of virus-induced disease
106). Effector caspases (such as caspase 3) function primarily to cause the morphological features of apoptosis. Specifically, activation of caspase 3 leads to the breakdown of several ...