Alzheimer's disease is a debilitating neurodegenerative disorder that afflicts an increasing part of our ageing population. An isoform of apolipoprotein E, a protein that mediates the transport of ...

Scientists led by Guojun Bu, Mayo Clinic, Jacksonville, Florida, believe they have found an important link between the E4 isoform of apolipoprotein E and insulin resistance in the brain. In the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 24 (June 13, 2017), pp. 6292-6297 (6 pages) Relative to the apolipoprotein E (apoE) E3 allele of the APOE ...

Make a Comment To make a comment you must login or register. References Paper Citations Kang DE, Saitoh T, Chen X, Xia Y, Masliah E, Hansen LA, Thomas RG, Thal LJ, Katzman R Genetic association of the ...

PURPOSEApolipoprotein B mRNA-Editing Catalytic Polypeptide-like (APOBEC) enzymes are mutagenic factors contributing to tumor progression and therapy resistance. However, the effects of APOBEC-induced ...

The most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels, researchers have found. Up to 15 percent of individuals possess the ...

Researchers exploring dementia-related proteins in the brain identified Apolipoprotein E (ApoE) as a key misfolded protein. About 25% of individuals, and 50% of individuals with Alzheimer disease ...

Human apolipoprotein E (apoE) promotes hepatitis B virus (HBV) infection and production, according to a study published Aug 8 in the open-access journal PLOS Pathogens by Luhua Qiao and Guangxiang ...

Unión-Caballero, A., et al. (2023). Apolipoprotein E gene variants shape the association between dietary fibre intake and cognitive decline risk in community-dwelling older adults. Age and Ageing ...

with slide / Researchers are making headway in the study of Parkinson's disease. Results of one study showed that people with ApoE-2 are 20% more likely to develop Parkinson's.

PLOS. "Targeting apolipoprotein E could be key to eliminating hepatitis B virus." ScienceDaily. ScienceDaily, 8 August 2019. <www.sciencedaily.com / releases / 2019 / 08 / 190808152453.htm>.