Growth Hormone-Releasing Peptide-2 (GHRP-2) is a synthetic hexapeptide that has garnered significant attention in the ...

Methods Two cardiac MRI cohorts were included: 2106 participants (median age: 65 years, 54% women) from the Multi-Ethnic Study of Atherosclerosis (MESA) and 2960 participants (median age: 64 years, 52 ...

In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the effects of astrocyte-derived human APOE isoforms in APOE-deficient mouse ...

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ki.se Objective To assess the contemporary prevalence of, and factors associated with angina pectoris symptoms, and to examine the relationship to coronary atherosclerosis in a middle-aged, general ...

This is valuable work with theoretical implications for possible mediation by MMP12 in the link between atherosclerosis and intracranial aneurysms, using Mendelian Randomization for causal inference.

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Greater decline in brain volume, particularly in older adults carrying the APOE-ε4 gene, a known genetic risk factor for Alzheimer’s These negative effects showed up even after accounting for physical ...

Low levels of slow-wave sleep were linked to a higher risk of cardiovascular disease, taking medications that can impact sleep, and having the APOE ε4 gene, which is linked to Alzheimer's. "We found ...

These patients had increased number of coronary arteries involved (p=0.04), and ≥50% coronary atherosclerosis/occlusion was numerically more common compared with MI-non-SLE controls (88% vs 66%; ...

Atherosclerosis (AS) is a chronic inflammatory disease characterized ... (85) reported that dapagliflozin treatment ameliorated aortic AS formation in streptozotocin-induced diabetic ApoE−/− mice. The ...