“Many of the observed associations linking greater sedentary time with brain health and cognitive outcomes were present in ...

These cDCs present brain-derived antigens to T cells sitting in the cervical lymph nodes. In ApoE4 carriers, CD8+ T cells more easily cross from the blood into the brain. In tauopathy mice, antigens ...

2020). In the CNS, TIM3 is predominantly expressed by microglia, where it cranks up further in female ApoE4 carriers. Variants in the gene have been tied to AD risk (Sep 2021 news). By way of ...

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"These findings suggest that above and beyond physical activity level, more sedentary behavior is still worse for brain health and cognition over time," Gogniat told MedPage Today ...

Unsurprisingly, it found that APOE4 carriers were likely to have more white matter loss; notably, however, those hewing to AHA lifestyles always showed reduced white matter loss regardless of ...

Annovis Bio Inc. (NYSE: ANVS) ("Annovis" or the “Company”), a late-stage clinical drug platform company pioneering ...

In calling for more clinical testing of vaccines in younger people and those who face a low risk of severe disease from Covid ...

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively ...

Implementing these [suggested] recommendations will help ensure that ApoE4 carriers receive safe, effective, and personalized treatment strategies that reflect their unique medical needs. These ...

Here, the authors use advanced microscopy techniques to reveal that apoE4 is less effective in ... and increased amyloid deposition in ApoE-ε4 carriers. A quantitative fluorescence-activated ...