Hematopoietic reprogramming reflects the selective and evolutionarily conserved engagement of transcription factor networks that encode innate immune memory in long-lived stem cells.
CD19 chimeric antigen receptor (CAR) T-cell therapy showed potential in treating patients with refractory systemic lupus erythematosus (SLE), with B-cell depletion and disease activity reduction ...
Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers such as ...
- Orelabrutinib, a highly selective CNS-penetrant, oral small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with best-in-class potential now in Phase 3 development for progressive forms of ...
Early broadly neutralising antibody responses against the E1E2 glycoprotein seem to be important for preventing persistence ...
Three scientists shared the 2025 Nobel Prize in Physiology or Medicine for their contributions to the field of immunology. Earlier today, it was announced that Mary E. Brunkow, PhD, Fred Ramsdell, PhD ...
Tumours exploit these pathways as a key immune evasion strategy.16 Immune checkpoint blockade, by removing inhibitory signals of T cell activation, allows tumour-reactive T cells to overcome ...
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