The most commonly used antibody fragment format is the Fab format, but it is difficult to produce in bacterial expression systems because of its large and complex structure.

This region is called the ''Fc (Fragment, crystallizable) region''. In this area are two heavy chains that contribute two or three constant domains depending on the class of the antibody.

Understanding these glycosylation patterns is just as important as analyzing other tools like labeled peptides, which are ...

Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability. Structure, 2017; DOI: 10.1016/j.str.2017.08.011 ...

RG7221 and RG7716 are representative products of CrossMab, both of which are anti-Ang-2 / VEGF bispecific antibodies. Its structure is based on the "knobs-holes" structure through the chain exchange ...

Discovery of antibody structure could lead to treatment for Crimean Congo Hemorrhagic Fever virus Study provides insights into fighting broad range of pathogen's viral strains Date: November 29 ...

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal ...

The Federal Circuit issued a decision in Baxalta Inc. v. Genentech, Inc., ___ F.3d __, 2020 WL 5048435 (Fed. Cir. Aug. 27, 2020) construing the terms “antibody” and “antibody fragment ...