Our study shows how a small antibody fragment can block fertilization by targeting ZP2, a key protein in the outer layer of the egg that is involved in both sperm binding and blocking polyspermy." ...

Wiesner first developed them more than 15 years ago and, in collaboration with Bradbury, published a 2018 study that found an antibody fragment-nanoparticle hybrid to be especially effective in ...

An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. ACS Chemical Neuroscience, 2023; DOI: 10.1021/acschemneuro.3c00455 ...

News Release 16-Mar-2023 Antibody fragment-nanoparticle therapeutic eradicates cancer Peer-Reviewed Publication Cornell University ITHACA, N.Y.

Immunosensors are widely used in immunoassays to detect antigens. One such immunosensor is a quenchbody (Q-body), which contains a modified antibody fragment with a quenched fluorescent dye. When ...

KaloBios Pharmaceuticals is to receive $35 million up front from Sanofi Pasteur as part of the companies’ collaboration to develop KaloBios’ Phase II-stage antibody fragment KB001 for treating ...

NI006 is a recombinant human anti-ATTR antibody that was developed for the removal of ATTR by phagocytic immune cells. Methods. In this phase 1, double-blind trial, we randomly assigned ...

An antibody that binds to fentanyl, reported recently in ACS Chem. Neurosci. (2023, DOI: 10.1021/acschemneuro.3c00455), is also scheduled to start clinical trials later this month.

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal ...