The first recipient of a gene-edited pig kidney died from cardiac causes 52 days after xenotransplantation. The world's first recipient of a gene-edited pig kidney died from cardiac causes within 2 ...

Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone ... myocardial fibrosis, ventricular arrhythmias, and ...

FIGURE 2. Summary of the interventions of cardiac fibrosis. Note: CAR, chimeric antigen receptor; NLRP3: nod-like receptor protein three; RAAS: renin-angiotensin-aldosterone system; SGLT2-i: ...

The vascular response to angiotensin I was blunted in the presence of aldosterone ... Clinically, the effect of aldosterone blockade on myocardial fibrosis can be demonstrated by measuring collagen ...

The patients were treated with β-blockers (n=27), calcium-channel blockers (n=10), disopyramide (n=1), angiotensin-converting ... We demonstrate that patients with fibrosis in myectomy specimens have ...

Ang II, angiotensin II; PDGFD, platelet-derived growth factor ... The increased miR-133 could inhibit cardiac fibrosis, cardiac hypertrophy, funny currents, and cardiomyocyte apoptosis and contribute ...

12 Thus, is it likely that elevated cardiac troponin concentrations during COVID-19 in many patients do not reflect significant new myocardial injury and fibrosis ... by entry through the cell surface ...

A discovery offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in ...

Not all scars are created equal. That's the conclusion of a new study by Weizmann Institute of Science researchers: They found that two distinct types of scars, referred to as "hot" and "cold," can ...