Amyloidosis represents a heterogeneous group of disorders defined by the extracellular deposition of misfolded protein fibrils, which can cause severe impairment in multiple organs. In the context ...

CAMBRIDGE, Mass., June 09, 2025--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNA interference (RNAi) therapeutics company, today announced that the European Commission (EC) has ...

Introduction Amyloidosis is characterized by the deposition of protein fibrils with a ß-sheeted structure. This structure is responsible for the insolubility of the protein fibrils, their ...

Indications In the EU, AMVUTTRA ® (vutrisiran) is indicated for the treatment of: hereditary transthyretin amyloidosis in adult patients with stage 1 or stage 2 polyneuropathy (hATTR-PN).

The current multi-center Phase 3 trial (NCT05184088) aims to further validate florbetaben (18F)'s efficacy in the diagnosis of cardiac amyloidosis, including the ATTR subtype.

Omaira Halwani; Diego H Delgado Disclosures Expert Rev Cardiovasc Ther. 2010;8 (7):1007-1113.

Alnylam has been a pioneer in hereditary ATTR amyloidosis, getting approval in 2018 for the first drug to treat the rare disease, and has now launched a digital companion to help patients track ...

The FDA has accepted two separate marketing applications for the drug – both for cardiomyopathy associated with the rare disease ATTR amyloidosis – and awarded a priority review for one of them.

Discover reviews, ratings, and trailers for Beauty and the Beast (2017) on Rotten Tomatoes. Stay updated with critic and audience scores today!

State Farm is the best company for home and auto insurance bundles, receiving five out of five stars in our analysis. Erie and Nationwide are also top picks, each receiving 4.7 stars. To determine ...

Whether you have cold feet and hands naturally or there's a cause that you need to remedy, here's what to know and what you can do about it.

Ciara and Russell Wilson welcomed their third baby together, daughter Amora Princess Wilson, in December 2023. She joins siblings Future Zahir Wilburn (born 2014), from Ciara's previous ...