I was constantly sweating." She was also retaining fluid. Elsie soon learned the cause - cardiac amyloidosis. "We used to think of it more as a rare disease," says Dr. Carly Fabrizio of Temple Health.

Drugs that treat a similar plasma cell disease, multiple myeloma, can sometimes be effective in people with AL amyloidosis. By far, the most important of these drugs is daratumumab (Darzalex), a ...

The phase III AFFIRM-AL study was a global, double-blind, placebo-controlled, time-to-event clinical trial that enrolled 207 newly diagnosed, treatment naïve patients with Mayo Stage IV AL ...

Topline results were announced from a phase 3 trial evaluating birtamimab in patients with amyloid light chain (AL) amyloidosis. Birtamimab is an investigational monoclonal antibody designed to ...

Spondylitis is a painful condition that impacts the spine, particularly the vertebrae and joints. It is prone to causing stiffness, pain in the neck or back, reduced mobility, and inflammation.

Art Still has ATTR amyloidosis, an inherited heart condition that dramatically impacts Black men and the former Kansas City Chiefs defensive end wants to raise awareness.

Another major contributor to inflammation in ankylosing spondylitis is interleukin-17 (IL-17). Like TNF-alpha, IL-17 is a type of cytokine that signals specific immune cells to activate ...

TNF Inhibitors May Cut Heart Risk in Ankylosing Spondylitis A nationwide observational study found that exposure to TNF inhibitors, but not IL-17 inhibitors, was linked to a lower risk for ...

EchoGo® Amyloidosis is an AI-based software-only medical device, which aims to improve early detection of Cardiac Amyloidosis, an underdiagnosed cause of heart failure. EchoGo® Amyloidosis sits on ...

DEAR MAYO CLINIC: My dad was diagnosed with cardiac amyloidosis shortly after his 70th birthday. It’s difficult to pronounce let alone understand. What is cardiac amyloidosis? Am I at risk ...

Wainua is an injectable medicine. Here’s how it treats hereditary transthyretin-mediated amyloidosis (hATTR).

What Kidney Problems Are Associated With Ankylosing Spondylitis? One type of kidney problem people with AS get is secondary renal amyloidosis. That’s when an abnormal protein builds up in organs ...