While healthy transthyretin moves hormones through blood and spinal fluid, misfolded versions of the protein form dangerous clumps in the heart and along nerves—triggering a progressive and fatal ...

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always ...

Alzheimer’s disease — which affects an estimated 7 million Americans — is notoriously difficult to detect, especially in its ...

There exists no ‘amyloid cabal’” in Alzheimer’s research, neurologist Dennis Selkoe writes in response to Charles Piller’s ...

Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,” Charles Piller looks how the amyloid hypothesis took over ...

Researchers from Osaka University found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid ...

Researchers from Osaka University find that peristaltic pump action and high shear flow forces promote amyloid nucleation.

A new biomarker test can detect early-stage tau protein clumping up to a decade before it appears on brain scans, improving ...

A Phase III trial evaluating nex-z in transthyretin amyloidosis with cardiomyopathy is underway, with plans for another ...