The FDA is considering using a noninvasive liver measurement as a surrogate endpoint for certain metabolic dysfunction-associated steatohepatitis (MASH) patients, a move that could speed up drug ...

It elucidates the series of events involving the dissociation, misfolding and aggregation of TTR proteins, resulting in the formation of amyloid fibrils. It also higlights various therapeutic ...

Transthyretin amyloidosis (ATTR) is caused by the misfolding and aggregation of the transthyretin (TTR) protein, leading to multi-organ damage. Two main forms exist: hereditary ATTR (ATTRv), linked to ...

The U.S. Food and Drug Administration (FDA) has approved Novo Nordisk's popular weight-loss drug Wegovy to treat a serious form of fatty liver disease. The approval makes Wegovy the only GLP-1 therapy ...

Liver King, the very red gentleman who receives what is perhaps the most liberal interpretation of the title “health and fitness influencer,” is in the middle of what can mostly be described as an ...

In 1980, Ludwig and colleagues described the histologic features of a newly identified chronic liver condition referred to as nonalcoholic steatohepatitis (NASH) and noted that the majority of the ...

Investors have struck a deal to buy a majority stake in HistoSonics, valuing the company whose noninvasive therapy for liver tumors shows promise in other diseases at $2.25 billion. An investor group ...

A quiet revolution in care is helping patients with cardiac amyloidosis, a form of heart failure that long stumped doctors. By Simar Bajaj When James Hicks, 75, was diagnosed with heart failure, it ...

Rayan Salih, MD, a third-year internal medicine resident with the Northeast Georgia Health System, who hopes to specialize in cardiology, presented the poster, “Double Trouble: Pregnancy Challenges in ...

At least 60% of liver cancers globally are preventable through risk-factor reduction, including obesity-linked metabolic dysfunction-associated steatotic liver disease (MASLD) and cases caused by ...

Without efforts to address some causes, including alcohol use and metabolic issues, the researchers warn that cases could nearly double by 2050. By Nina Agrawal Liver cancer kills more than 700,000 ...