Baxdrostat is a highly selective, second-generation, nonimidazole aldosterone synthase inhibitor; 100 times less baxdrostat ...

All individuals with hypertension should be screened for primary aldosteronism (PA), according to a clinical practice guideline.

Even in people without high blood pressure, subclinical primary aldosteronism is linked to a significantly higher risk for ...

Aldosterone helps balance blood levels of sodium and potassium, researchers said. Levels that are too high can cause people ...

Just like any other profession, even healthcare professionals can often make mistakes like missing symptoms or misdiagnosing ...

A phase 2 trial evaluated the efficacy and safety of lorundrostat in hypertensive patients with chronic kidney disease (CKD) and albuminuria.

Aldosterone is a steroid hormone secreted by the adrenal glands, which sit above the kidneys. Its main role is to regulate salt and water in the body, and so it plays a central role in controlling ...

Increased levels of aldosterone are independently associated with a greater risk of type 2 diabetes, with the effects particularly notable in certain ethnic groups including African Americans and ...

Aldosterone, a hormone produced by the triangular adrenal glands, might be the key target. In the observational study, researchers analyzed health data from 3,680 people with chronic kidney ...

OBJECTIVE: To evaluate the relationship between insulin, the renin-aldosterone system and blood pressure in obese subjects. DESIGN AND METHODS: A cross sectional study of a group of severely obese ...

Aldosterone is associated with an increased risk of chronic kidney disease progression and the development of end-stage kidney disease, according to data published in the European Heart Journal ...

The effects of aldosterone and mineralocorticoid receptor (MR) blockers on presympathetic neurons in the rostral ventrolateral medulla (RVLM) are well studied. To directly investigate whether ...