All things Jaguars: Latest Jacksonville Jaguars news, schedule, roster, stats ... blood cells multiply uncontrollably in the bone marrow. The onset of APL can be sudden, but treatment has proven ...

Acute Promyelocytic Leukaemia (APL): A subtype of acute myeloid leukaemia characterised by the presence of the PML-RARA fusion gene, leading to a block in myeloid differentiation.

Acute promyelocytic leukaemia (APL) represents a unique and once highly fatal subtype of acute myeloid leukaemia that is now considered among the most curable forms of haematological malignancies.