Iptacopan targets one of the major proteins involved in the enzymes of the alternative pathway of complement, explains Carla Nester, MD, of Stead Family Children's Hospital.

Meaningful engagement: Driving clinical collaboration and outcomes Another key component of clinical embedded healthcare navigation is the capacity to drive meaningful engagement with both patients ...

Denifanstat showed positive Phase 3 results in acne, meeting all goals with strong safety, as Sagimet pushes ahead with a second FASN inhibitor trial.

Denifanstat met all primary and secondary endpoints versus placebo Denifanstat was well tolerated Oral FASN inhibitors offer a novel mechanism of action for the potential treatment of moderate to ...

Ascletis Announces Phase III Trial of Denifanstat (ASC40), a First-in-Class, Once-Daily Oral FASN Inhibitor for Acne, Meets All Endpoints ...

Traditionally within the purview of rheumatology, gout can appropriately be managed by nephrologists for patients with chronic kidney disease, according to experts who spoke with Healio ...

About BJT-188 BJT-188 is a preclinical, liver-targeted fatty acid synthase (FASN) inhibitor currently under investigation by Bluejay Therapeutics for the treatment of metabolic dysfunction ...

Carla Nester, MD, MSA, FASN, is coinvestigator for the ongoing APPEAR-C3G trial (NCT04817618), data from which were used to support the FDA’s recent approval of iptacopan (Fabhalta; Novartis) in ...

FORT COLLINS, Colo. — Two men died and a juvenile was arrested after a shooting outside the Foothills Mall in Fort Collins Saturday evening. Fort Collins Police said at around 5 p.m., a caller ...

Sonia Friedman has “created her own theater studio system,” balancing big properties like “Harry Potter” and “Stranger Things” with more prestige work by Stoppard and Sondheim.