This is the second of a two-part note, which covers: * What are GLP-1 receptor agonists? * Which were the first GLP-1s approved for type 2 diabetes (T2D)? When were they approved? Who makes them? Are ...

This is the first of a two-part note, which covers: * What are GLP-1 receptor agonists? * Which were the first GLP-1s approved for type 2 diabetes (T2D)? When were they approved? Who makes them? Are ...

Executive summary * This week's note is about Dr Malcolm Kendrick's new book called The Clot Thickens. * Malcolm has been trying for 30 years to understand and explain what really causes heart disease ...

Introduction (Jump to the Executive Summary at the end if you don’t want the full monty). This is a review of a book written by James & Hannah Yoseph entitled How statin drugs really lower cholesterol ...

* Last week's note reviewed a Korean population study, which led to headlines such as " Taking statins could slash dementia risk." The claims were not robust. * This week's note reports findings from ...

Introduction Food (noun): “Substance taken into body to maintain life and growth; nutriment” (Ref 1). In a world where food has become huge business ... an emotional crutch ... one of the greatest ...

* This note summarises what carbohydrates are, from fructose to fibre. * It briefly looks at the role carbohydrates have played historically – feeding and growing the population and freeing people up ...

An excellent presentation was posted on Youtube on 12 February 2017 (try this if the first link doesn’t work). Just 22 minutes long, it is well worth a watch. The speaker, Professor Salim Yusuf, is a ...

* I read a book called “Burn: The misunderstood science of metabolism” by Dr Herman Pontzer. Pontzer had lived with and studied the Hadza – a modern hunter-gatherer people living in northern Tanzania.

Executive summary * The National Institute for Clinical Excellence (NICE) is the organisation in the UK that sets medical guidelines for every drug, every intervention, and every procedure. * NICE ...

Executive summary * The official positions from the World Health Organisation (WHO), the US Centres for Disease Control (CDC), the US Surgeon General and the UK Deputy Chief Medical officer are ...

Executive summary * A study generated headlines about the relationship between the incidence of type 2 diabetes (T2D) and intermittent fasting/skipping breakfast. It wasn't about intermittent fasting ...