My PhD supervisor, Bob, kindly shared his CV with me and recommended that I peruse other scientists’ research webpages for theirs. Sure enough, many researchers in my field had a link next to their ...
The protein homeostasis (proteostasis) network (Balch et al, 2008), consisting of a collection of molecular chaperones, ...
The enteric nervous system (ENS), the largest division of autonomic nervous system, is a tantalizing frontier in neuroscience. With the advent of single-cell transcriptomics, the ENS has been ...
Inherited metabolic diseases are rare monogenic conditions that disrupt biochemical pathways, affecting energy production and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neuronal presynaptic terminals contain ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.
Image data are universal in life sciences research. Their proper handling is not. A significant proportion of image data in research papers show signs of mishandling that undermine their ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Substrate specificity determines protease ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Specific and non-invasive diagnostic tools are ...
LINE1 (L1) retrotransposons have gained notoriety for their involvement in a slew of pathologies. While improper de-repression of L1 transcription may drive disease, mammalian cells have coopted L1 ...
In this report, we describe a unique human UBL‐type modifier named u biquitin‐ f old m odifier 1 (Ufm1) that is synthesized in a precursor form consisting of 85 amino‐acid residues. We also identified ...
Autophagy is a major pathway for delivery of proteins and organelles to lysosomes/the vacuole, where they are degraded and recycled. Autophagy plays an essential role in differentiation and ...
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