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The US administration has extended its line of attack on academia from US federal research to private universities. The abuse ...

Although student mobility is being restricted in a less dramatic fashion than currently in the USA, the impact on science ...

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

imageimageThe ALS-associated VAPB P56S mutation disrupts ER–mitochondria associated membranes (ER-MAMs) and leads to mitochondrial stress and activation of the integrated stress response (ISR). ISR ...

Lymphedema is a chronic lymphatic disorder characterized by persistent tissue swelling, pain, and recurrent infections, often secondary to cancer treatment, surgery, or obesity. Obesity-associated ...

Silencing evolutionary young retrotransposons by cytosine DNA methylation is essential for spermatogenesis, as failure to methylate their promoters leads to reactivation, meiotic failure, and ...

Lysophosphatidylinositol (LPI) bioactive lipids are implicated in energy homeostasis and metabolic disorders, but their roles in insulin signaling remain unclear. This study reveals hepatic ...

Therefore, the aim of this study was to perform an extensive multi-omic analyses on cryopreserved pre-mortem human left ventricular myocardium to uncover the influence of DM in end-stage HF and to ...

The traditional treatment for systolic heart failure compromise heart contractility resulting in reduced cardiac output and exacerbate the symptoms. The newly developed drug-like compound (BR43) ...