The variable response to cancer immunotherapies highlights a critical gap in our ability to predict and monitor treatment efficacy. To address this, there is an urgent clinical need for advanced ...

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. After the use of liver-directed therapies, it is challenging to differentiate between nonviable tumor and ...

Clinical molecular imaging with PET has an evolving role in the diagnosis and treatment of left ventricular assist device (LVAD)–specific infection. We analyzed the added value of parametric ...

Around 20% of men with prostate cancer develop metastatic disease during the course of their disease. Accordingly, discovering and developing new potent treatment strategies for metastatic prostate ...

Learning Objectives Understanding common pitfalls is important for the radiologist evaluating cancer patients. We present 7 cases that demonstrate interesting examples of pitfalls in PET/CT imaging of ...

There is a pressing need for improved standardization of terminology and data in nuclear medicine. The field is experiencing unprecedented growth, driven by advances in radiopharmaceutical therapy ...

The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...

α-particle emitters are emerging as a potent modality for disseminated cancer therapy because of their high linear energy transfer and localized absorbed dose profile. Despite great interest and ...

Foregoing Nonclinical Dosimetry Studies to Support First-in-Human Studies of Certain PET Radiopharmaceuticals ...

Glypican-3 is a proteoglycan that is overexpressed on the surface of hepatocellular carcinoma (HCC) cells ([1][1],[2][2]). Recently, [68Ga]Ga-RAYZ-8009 was introduced as a promising PET tracer for HCC ...

251576 Introduction: The N-methyl-D-aspartate (NMDA) receptor is a pivotal component of the heterotetrameric glutamate-gated ion channel in the central nervous system (CNS) and mediates key ...

Prostate cancer (PCa) is a leading cause of cancer deaths, making effective early detection, precise staging, and monitoring of biochemical recurrence crucial. Next-generation prostate-specific ...