Background Plant-derived exosome-like nanoparticles (PELNs) have been considered to have great prospects in the treatment of ulcerative colitis (UC) as they serve as a natural nano-drug carrier that ...

A 65-year-old previously well man presented with 3 weeks of generalised abdominal pain and diarrhoea up to three times per ...

11 Liver Unit, St James's University Hospital, Leeds, UK Non-alcoholic steatohepatitis (NASH) is an increasing cause of liver disease necessitating liver transplantation. In patients with advanced ...

Introduction The Rome Foundation stated recommendations in 2016 to report confounding factors in clinical trials concerning functional gastrointestinal disorders (FGIDs) [1]. The aim of our study was ...

Professor M Trevisan, Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, 270 Farber Hall, 3435 Main Street, Buffalo, New York 14214–3000, USA. Email: trevisan{at ...

Background Early detection of colorectal cancer (CRC) is crucial for improving the survival rates of patients. Objective We aimed to develop a novel strategy for early CRC detection using the ...

Correspondence to Professor Jingmei Jiang, Department of Epidemiology and Biostatistics, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medical Sciences, ...

Correspondence to Professor Siew C Ng, Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong; siewchienng{at}cuhk.edu.hk; Dr Ruth Chan, Applied Biology and Chemical ...

The effects of loperamide on net solute and water absorption, and prostaglandin E2 (PGE2) and cholera toxin-induced secretion were studied in the rat jejunum using an in vivo steady-state perfusion ...

Introduction Steroids have been an established treatment in flares of inflammatory bowel disease (IBD) for the past 50 years. Whilst evidence exists to guide the initial dose of these drugs, data ...

7 Institute of Anatomy and Cell Biology, Martin-Luther University Halle-Wittenberg, Halle, Germany 8 Institute of Anatomy, University of Leipzig, Leipzig, Germany Objective Bacterial translocation to ...

Gastroparesis is defined by delayed gastric emptying (GE) and symptoms of nausea, vomiting, bloating, postprandial fullness, early satiety and abdominal pain. Most common aetiologies include diabetes, ...