A 51-year-old man with hypertension had previously been admitted to our cardiothoracic unit with a type A aortic dissection (Stanford classification) and had undergone emergency surgery with partial ...

Identifying novel molecular drivers of disease progression in heart failure (HF) is a high‐priority goal that may provide new therapeutic targets to improve patient outcomes. The authors investigated ...

From the Cardiac Muscle Research Laboratory (M.J., D.A.B., S.N., P.T., C.S.A., R.L.) and the Myocardial Biology Unit (D.B.S., W.S.C.), Boston University School of ...

Heart failure is a global public health issue that is associated with increasing morbidity and mortality. Previous studies have suggested that mitochondrial dysfunction plays critical roles in the ...

From Institute Dante Pazzanese of Cardiology (J.E.S., A.A., F.F., A.C.S., L.F.T., L.A.M., A.G.M.R.S.), São Paulo, Brazil; University of Florida, Shands-Jacksonville ...

From the Cardiovascular Division, Department of Medicine (G.W.D.K., Y.W., Y.F., S.M., K.Y., R.T.L.), Brigham and Women’s Hospital, Harvard Medical School, Cambridge ...

New Cornerstone Investigator Institute, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of ...

From the Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio. Because accurate selection of cardiac transplant recipients remains such a challenging issue and in ...

From the Departments of Emergency Medicine (I.S.), Medicine (G.N.), and Epidemiology and Community Medicine (G.W.), Clinical Epidemiology Program (V.D.M., L.N., J.B ...

An interesting target for cardiovascular drug development is Lp-PLA2, an enzyme that may act in the twilight zone between lipoprotein metabolism and inflammation. Lp-PLA2 is produced by macrophages ...

From the Departments of Internal Medicine III (A.A., C.H., C.U., A.O., A.M.Z., S.D.) and Neurology (S.L.), J.W. Goethe University, Frankfurt, Germany; Weizmann ...

From the Department of Medicine, University of Washington, Seattle. Dr Pennathur is currently at the Department of Medicine, University of Michigan, Ann Arbor. From the Department of Medicine, ...