For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted ...
Why then did so many cell-cycle mutants of the yeasts arrest not just a single event of the cell cycle but all subsequent downstream events as well? Many gene products have now been identified ...
Figure 2: Nocodazole-mediated cell cycle arrest of adherent HeLa cells, as measured using a laser-scanning microplate cytometer (Acumen e X3). Nuclear-ID Red DNA stain is a far-red–emitting dye ...
Previous studies revealed a positive correlation between O-GlcNAcylation and tumor growth via the stabilization of target proteins, with O-GlcNAcylation transferase (OGT) being the only enzyme capable ...
HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.
A murder arrest affidavit released Tuesday shows ... Brad shut off his cell phone and began an "on/off" cycle of lockdown mode of the cell phone. Shortly after: Vehicle location data showed ...
New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.
I was freaking out because I somehow went from driving into the golf course to a jail cell and I still don't really know how that happened exactly," says Scheffler in a voiceover as his arrest ...