Background Subcutaneous (SC) administration is the preferred parenteral opioid route in palliative care, while intravenous infusion may allow faster titration. Comparative evidence remains limited.

Virtual reality interventions for mental health and well-being in palliative care: systematic review and narrative synthesis – outcomes, techniques, processes and mechanisms ...

The Terminally Ill Adults (End of Life) Bill is currently under debate within the UK Parliament. If passed, the bill will affect individuals living in England and Wales, providing a legal framework ...

Objectives Venous thromboembolism (VTE) is common in advanced cancer. Guidelines suggest that indefinite anticoagulation be considered for patients with ongoing active cancer. There are no data on the ...

Introduction Approximately 1 in 3 hospital inpatients may be in their last year of life in Scotland (Clark, 2014); however no data exists for England. This study aimed to review outcomes of admissions ...

Background Pain is the most common presenting symptom of patients referred to palliative services. The effective management of pain is therefore paramount to any palliative service. The SOCRATES ...

Home-based oncology palliative care is racing against time. In Florence, Italy—a city with approximately 364 073 inhabitants in 2024, with 990 527 in its metropolitan area1—a resolute team of four ...

Objectives Supportive and palliative care include non-oncology settings where patients suffer from pain and quality of life-related concerns. Integrative medicine plays important roles in supportive ...

Background/objectives Handgrip strength is a critical indicator of overall health, particularly in older adults, and is associated with frailty, sarcopenia and risk of adverse health outcomes. Precise ...

Hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels control neuronal firing thresholds. Together with sodium channels, they accumulate at sites of nerve injury, creating ectopic foci of ...

Orthostatic hypotension is a relatively common medical diagnosis and can be debilitating for the patients it affects. There is a range of treatment options, though only one medication is licensed in ...

Objectives End-of-life decisions in intensive care units (ICUs) are complex, influenced by patient severity, treatment efficacy and resource constraints. This study assessed the predictive value of ...