Poor saliva control (sialorrhoea) represents a considerable burden to paediatric patients with neurodevelopmental ...

Usually, when life-saving treatment is withdrawn from children with the agreement of their parents, there is no necessity for any legal involvement or intervention. In the small number of cases where ...

Objective To determine the safety of ciprofloxacin in paediatric patients in relation to arthropathy, any other adverse events (AEs) and drug interactions. Methods A systematic search of MEDLINE, ...

Correspondence to Dr Alison Salt, Neurodisability Service, The Nurses Home Building, Great Ormond, Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK; alison.salt{at}gosh.nhs.uk ...

Databases are electronic filing systems that have been set up to capture patient data in a variety of clinical and administrative settings. While randomised controlled trials are the gold standard for ...

Objectives Pica is a problematic and little-studied health concern in children with sickle cell disease, defined as the age-inappropriate consumption of non-nutritive materials. 1 Pica behaviours can ...

BACKGROUND Cause specific research on death certification in chronic disease has rarely involved cerebral palsy. AIMS To evaluate cause of death information in people known to have cerebral palsy by: ...

Correspondence to Dr Mary E Ramsay, Department of Immunisation, Hepatitis and Blood Safety, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK; Mary.ramsay{at}phe.gov.uk By 2010, the ...

Clinical, immunological, and intestinal studies on 26 children with IgA deficiency in the age range 2 to 16 years are reported. 9 of these children were suffering from autoimmune disease, namely ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Background: Cerebral palsy presents with a range of severity of cognitive, motor, and sensory disabilities, which might affect survival. Aims: To quantify the effects of motor, cognitive, and sensory ...

Mortality outcomes of children and young people who have spent time in care: evidence from Children’s Health in Care in Scotland, a population-wide administrative data cohort study (5 June, 2025) ...