Chicago White Sox relievers have a 2.75 ERA heading into Monday’s series opener against the Tampa Bay Rays, the second-best mark in baseball since June 19.

The Pittsburgh Pirates took a solid, early lead before faltering later on with a poor bullpen performance in a 10-4 loss to the Chicago White Sox a

Edgar Quero also homered for Chicago, taking Pirates starter Bailey Falter (6-5) deep in the first inning as the White Sox jumped on Pittsburgh early to win for just the 12th time in 48 road games this season. Andrew Benintendi and Colson Montgomery added two hits and drove in two runs apiece for Chicago.

The Tigers are favored (-147 moneyline odds) when they visit the Pirates (+123). The scheduled starters are Casey Mize (9-3) for the Detroit Tigers, and Mitch Keller (3-10) for the Pittsburgh Pirates.

CBS Sports brings you live coverage, scoring, expert picks and stats for the MLB matchup between Chicago White Sox and Tampa Bay Rays on July 21, 2025

View news about the Chicago White Sox vs. Tampa Bay Rays game played on July 21, 2025 including player news, injury news, predictions, analysis and more.