The Arizona Cardinals open their three-game preseason slate against Patrick Mahomes and the Kansas City Chiefs at State Farm Stadium in Glendale.

The Arizona Cardinals opened the preseason with a 20-17 win over the Kansas City Chiefs Saturday night at State Farm Stadium. They fell behind 14-3, but backup quarterback Jacoby Brissett threw two touchdown passes in the second quarter,

ARIZONA -- The Arizona Cardinals play host to the Kansas City Chiefs later today in the first of three preseason matchups for the organization. After a tough training camp concluded earlier this week, Jonathan Gannon's crew will have the opportunity to hit someone other than themselves for the first time in 2025.