The TDP-43 field now has both wild-type TDP-43 and mutant mouse models, but “I would not say they are a matched pair,” Baloh said. They are closer than apples and oranges, more like “oranges and ...

27 Oct 2020. Creating better, more reliable rodent models of Alzheimer’s disease has been a struggle for researchers. On October 19 in Molecular Neurodegeneration, scientists led by Bart De Strooper ...

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, is a fatal neurodegenerative disorder that affects approximately 350,000 people worldwide. 1 Most cases of ALS have no identified ...