Mdm2 negatively regulates tumor suppressor p53 via binding to the transactivation and the DNA-binding domains of p53. Now work reveals a novel interaction between the N-terminal domain of Mdm2 and ...

The allosteric binding of MSI-1436 to the intrinsically disordered C-terminal region of PTP1B promotes a conformational change to generate a compact inactive structure, validating the use of MSI ...

Terminus is the ABM and go-to-market platform to keep your eyes on.” The investment by Great Hill Partners brings Terminus’ total funding to $125M.

The B.C. government has approved the continued construction of a new pipeline project that could supply natural gas to a proposed floating liquefied natural gas export terminal off B.C.'s North Coast.

B.C. Premier David Eby says he wouldn't be opposed to a pipeline to the northern coast if it were proposed by a private backer. Alberta Premier Danielle Smith says the project could generate billions.

The B.C. government has approved the continued construction of a new pipeline project that could supply natural gas to a proposed floating liquefied natural gas export terminal off B.C.'s North Coast.