Levels of the hormone increase with disease severity, a new study has found. Plasma levels of insulin-like growth factor 1 (IGF-1) could give clinicians a better understanding of whether a patient ...

Women with high levels of insulin-like growth factor 1 (IGF-1) may be at increased risk for breast cancer, according to results of a study that used both epidemiological techniques as well as genetic ...

The original methods for targeting the IGF-I receptor in experimental animals were antisense strategies and dominant-negative mutants of the receptor. They are obsolete. Several antibodies to the ...

Vitamin D and insulin-like growth factor-1 (IGF-1) are involved in a complex interplay that may have implications for growth hormone dosing, researchers found. In a review of the literature, patients ...

Now UAB researchers, led by Guanlan Xu, Ph.D., and Shalev drilled down further into the mechanism underlying verapamil’s beneficial effect. In a paper published in Diabetes, they show that, in Type 1 ...

November was a dreary month for those who had high hopes for insulin-like growth factor-1 as a treatment for neurodegenerative disorders. Though IGF-1 still has potential, therapies based on the ...

Puberty is triggered by pulsatile release of GnRH from specific nerve cells in the the brain. What signals tell these nerve cells to release GnRH in this manner has not been determined, although it ...

Figure 1: Characterization of MLC/mIgf-1 transgenic mice. Figure 4: Intracellular signalling in MLC/mIgf-1 transgenic muscle. Figure 5: MLC/mIgf-1 expression attenuates age-related genetic changes ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. The PATHFNDR-2 trial enrolled adults with acromegaly who ...

The use of systemic IGF-1 has been shown to attenuate the postburn hypermetabolic response and improve burn wound healing. Local IGF-1 gene therapy, however, promotes re-epithelialization in the burn ...

Since its discovery over 50 years ago, the biological aspects of insulin-like growth factor-1 (IGF-1) have been determined to be extensive. Ranging from cell proliferation, cell differentiation and ...