Cushing's syndrome and its pituitary variant, Cushing's disease, represent complex endocrine disorders characterised by chronic excessive glucocorticoid exposure. This hypercortisolaemia may be the ...
Background: Cushing's disease is very rare in the paediatric population. Although uncommon, corticotroph hyperplasia causing Cushing's syndrome has been described in the adult population, but appears ...
Agents that directly lower ACTH secretion by a pituitary adenoma represent an attractive option for the treatment of Cushing's disease, as these drugs directly target the pathogenesis of disease.