You lose plenty of features here from a YubiKey, and a serious downside is the lack of Bluetooth and NFC support. This completely limits mobile device connectivity, especially for the USB-A key.

You could store your TOTP codes on your YubiKey, and back them up elsewhere (i.e. on a USB drive kept securely ... Consider ...

At the University of Bristol, we support YubiKey security keys. To set up your security key, you will need a computer or laptop with a USB-C port. Click 'choose USB device'. Plug your security key ...

The carrier began adopting Yubikey ... form of a USB drive, that taps public-key cryptography to authenticate the user’s logins. The result will generate and store the private authentication key for a ...